It looks like that is only 3 conductor wire and you mentioned your strip has 5 pads, right? If so, it would 'work' but you'd need to add a couple more wires or look for "5 conductor wire." It also seems pretty expensive for what it is and doesn't even mention what gauge wire they're using.

I don't know the conversion rate, but this stuff is only $0.74 per meter for what is probably the exact same wire (just different color)

Not very long. I have noticed a bit of flickering by the 3rd reel when using multiple segments. I plan on injecting some power at the start of the 3rd reel and have 20g (https://www.amazon.com/dp/B0829NPHF3?psc=1&ref=ppx_yo2ov_dt_b_product_details) wire arriving today.

Fire is my obvious concern. Where this will be kept will also have a wall switch attached, so the wall switch will be turned off when not in the room. Having said that, below is what I was planning on configuring in WLED.

LED Voltage: 5V efficient (35mA)

Length: 390

Enabled Limiter to 4000mA

With those settings it suggests 5V 14A supply (for most effects, ~5A is enough). Not sure what that means exactly.

The drawing above is how i planned on hooking things up (minus the fuse i guess). I think i will need 1 more modification, which is to have a sacrificial pixel to keep the data closest to the ESP, and then route data and power to the start and to the 3rd reel if that makes sense.

It doesnt seem like this should be much of an elaborate setup. I would image most would look to use more than 1 reel since they are only 16' long. Is there a good place i can use a multi-meter to test or look at power to make sure I'm not pulling more than necessary?