Below is what I have been using. Is the effect localized? The answer is yes and no. Wherever you rub the lotion the effects will be more strongly felt, however you can apply it to your hands and still receive the benefits in other areas of your body. For me a little goes a long way. If I apply too much then I get some unwanted side effects like a little anxious or a feeling of uphoria (buzzed feeling). I typically apply about a half gram to my hands and then rub it into the back of my hamstrings every morning. I came up with this routine through trial and error. You will most likely need to experiment to find what works best for you. https://www.amazon.com/Magnesium-Unscented-Relaxation-Overworked-Zechstein/dp/B09PVMTM9W?pd_rd_w=EEJGM&content-id=amzn1.sym.94349326-ca8a-4b0d-94f0-6931485b8573&pf_rd_p=94349326-ca8a-4b0d-94f0-6931485b8573&pf_rd_r=8HBCSE6TASJHCBVP7YGH&pd_rd_wg=8gQi4&pd_rd_r=918b0046-245a-4005-8af5-256477ba0fe9&pd_rd_i=B09PVMTM9W&psc=1&ref_=pd_bap_m_rp_27_sc