I guess so, you might want something like this https://www.amazon.com/Mayflash-Wii-Classic-Controller-Adapter/dp/B0089O4EB0
Including a usb hub like this https://www.amazon.com/ANDTOBO-Micro-Adapter-Power-Devices/dp/B083M1S6QT
— !! First make sure the emulator you are using supports 4players! :o !!
But yes, it is possible https://www.reddit.com/r/miniSNESmods/comments/102ucmk/4_player_snes_games/
[2 Pack] ANDTOBO 2-in-1 Micro USB... https://www.amazon.com/dp/B083M1S6QT?ref=ppx_pop_mob_ap_share