I was going to go with something like this, with the plan being to use the bottom XT60 one to route the AC current down to the PSU and then the top XT60 bringing DC back in, but as I got it closer and closer to having the design finished, I started worrying more and more about "idiot me" and accidentally reversing which was which.
I've settled on a simpler setup and I'll just re-use the rocker switch built into the case to control power to the main board.
Using 12 AWG high temp wire from the PSU to the Mini should let me safely push up to 30 amps max, and then inside the mini I can branch off multiple 16 awg wires from the XT60 to power the heater bed, mainboard, and whatnot.
Then on the front part of the panel, I'm going to add a toggle switch for controlling the parts fan.
Of course, writing this got me thinking, so here's what the current idea for the left side looks like... and on the back you can see there's a lot of reinforcement for the XT60 plug because of the amount of force to connect them.