Those fleas were manufactured by 4th Division of "Unit 731" AKA "Water Supply and Prophylaxis Administration of the Kwantung Army" AKA "Epidemic Prevention and Water Purification Department" between 1935-1944 in Northeast China (Pingfang District/Harbin to be exact).
12 former members of the Japanese armed forces were put on trial during 25-30.12.1949 in Khabarovsk/USSR charged with preparing and employing the bacteriological weapon.
Soviet scientists estimated that the unit can produce 300 kg of plague bacteria per month using 4.500 special incubators for the breeding of fleas on rodents at their peak, based on testimonies and preliminary investigation reports.
Here is a mind blowing detail on those special incubators from the testimony of Chief of the "Veterinary Service" of said army; Major General of the Medical Service Kawashima Kiyoshi:
This division had high-capacity equipment, divided into two sections, each of which could produce germs independently. The main equipment of the first section consisted of four boilers, each of one-ton capacity, for the preparation of the culture medium for the bacteria, and 14 autoclaves for sterilizing the medium, each 3 metres long and 1.5 metres in diameter. Each autoclave could hold 30 cultivators of a special design invented by Ishii, the Chief of Detachment 731. This first section had two cooling chambers for the medium, each of which could hold 100 cultivators simultaneously. This section also had five thermostats with a total capacity of 620 Ishii cultivators.
The second section had two boilers of two-ton capacity each, eight autoclaves, each capable of containing 60 cultivators, and other equipment.
The division also had a special refrigerator for preserving the finished “product.”
Sources:
"Materials on the Trial of Former Servicemen of the Japanese Army Charged with Manufacturing and Employing Bacteriological Weapons", Foreign Languages Publishing House, 1950
https://archive.org/details/MaterialsOnTheTrialOfFormerServicemen/page/n1/mode/2up
Unclassifed "Top Secret CENTRAL INTELLIGENCE GROUP, CINCFE Tokyo/Japan message" dated 27.06.1947
https://www.cia.gov/readingroom/docs/ISHII%2C%20SHIRO_0005.pdf
Unclassifed "Secret Field Information Report" dated 31.01.1957
https://www.cia.gov/readingroom/docs/ISHII%2C%20SHIRO_0011.pdf
Related books:
Unit 731: The Forgotten Asian Auschwitz (Uncovering Unit 731 Book 1)
https://www.amazon.com/dp/B07NRPC4TS
Marutas of Unit 731: Human Experimentation of the Forgotten Asian Auschwitz (Uncovering Unit 731 Book 2)
https://www.amazon.com/dp/B083LYJ66B
The Khabarovsk War Crimes Trial: Unearthing Biological Warfare in WWII
https://www.amazon.com/dp/B082XPLS48
Seeking Justice for Biological Warfare Victims of Unit 731: Evidence Collected by Wang Xuan
https://www.amazon.com/dp/B083Q224DV