If you're looking for the best bang for your buck, the small handle with 3 interchangeable needles is the way to go. I have relatively big hands (Large, and sometimes XL with gloves), and it is still comfortable.

I was able to punch up to #4 worsted weight with the smaller punch needle handle, with interchangeable needles, on the biggest needle. But I do not suggest going higher than DK withe the smaller handle.

The bigger handle 4mm works for #4 worsted weight BETTER and I can see it POSSIBLY (unsure) with 1 size up.

Have yet to try out the biggest (5.5 mm). I read it was mainly for chunky yarn.

I haven't attempted bigger yarn than #4 weight on any of the.

The link below is the worsted yarn I used, if that'll help with weight reference.

Knit Picks Wool of The Andes Worsted Weight Yarn (10 Balls - Rainbow) https://www.amazon.com/dp/B01M3SO62B/ref=cm_sw_r_apan_glt_i_F2FSY4EJGNPFHKRSFQFT?_encoding=UTF8&psc=1