The Tyan S7012 are a good build. I make a few ZFS file servers out of them every year, but few notes.

-They originally came with series 5500 intel support only. To get 5600 support, you will have to upgrade the firmware. So I recommend you buy a pair of L5520 CPUs when you get the board, they are super cheap quad core CPUs that a pair sells for around $5 now.

-The South bridge gets hot, some boards come with high profile heat sinks, but not most of them. If your build is not in a high air flow case consider placing a 40mm fan on the heat sink. This will help with system stability.

-It comes with only 5 PCIe x8 open ended slots, (some are only x4) It is nice since you can place larger cards into the slots (all PCIe should be open ended) but be careful in slot one, the rear components may stop you from placing a large card in them.

passmark of 26,104

No wonder you need water cooling, a 150W CPU needs that. Over all nice. Far more than I would spend, but I'm a bit on the cheap side.

I Purchased https://www.amazon.com/Asus-Hyper-M-2-x16-Card/dp/B0753JTJTG, for the heck of it. If it does not suit my needs I figured I can return or resell it and get most of my money back. My main issue is going to be installing it. Both my PCIe 3.0 x16 slots are full of video cards, and my only other option is the x4 slot that my NVMe card is currently sitting in. I am guessing a I may end up upgrading my board soon or I will most likely pull out my sound card and end up installing a PCI one instead. I have a few LGA 2011 boards, but I just spent a week building my current setup and I don't want to rip it apart. -_-

How well did this work for you? https://www.amazon.com/Asus-Hyper-M-2-x16-Card/dp/B0753JTJTG, I have been looking for a way to get a lot of m.2 nvme drives into a system, but most of the setups I see start at $199 and go upto $500. I have found this card for as little as $50 and I am curious how well it works. If I do end up with it, I will most likey do a software RAID instead of the hardware intel raid that only works with intel SSD that this card supports.