Oh, these are a major suck fest! I slather on some diaper rash cream. I like Resinol (available at Amazon, I've never seen it at a brick and mortar store). It's supposedly also a topical analgesic, but I don't really feel a difference. But it definitely helps with the friction and stays on pretty well even without a bandage (it'll get pink stuff on your clothes/bedding, but washes out just fine).