Yes, The DC-DC converter, something like this:
https://www.amazon.com/Yeeco-Converter-Adjustable-Transformer-Stabilizer/dp/B074J9D278/ref=sr_1_8?dchild=1&keywords=50v+dc+to+dc+buck+converter&qid=1622010839&sr=8-8
I might not be using the right terminology though, but as voltage differences increase (50V -> 1.075V for the CPU), the waste heat also goes up.