I have big boobs and am uncomfortable going braless at home. When I'm not sleeping, I wear Hanes Cozy Bra. My lounge clothes are usually a tank top, rayon kimono or cotton cardigan if it's cooler, with soft pants, leggings, or shorts. In the winter I add a long sleeved thermal shirt. In that outfit, I'm comfortable stepping outside for the mail or dealing with a delivery dude.
I make sure everything fits. If it gets ripped or hopeless stained, I get rid of it.